Cabergoline Treatment University Hospitals Sussex NHS Foundation Trust
Before administration of cabergoline, pregnancy should be excluded. Should pregnancy occur during treatment, cabergoline is to be discontinued. As with other ergot derivatives, pleuritis, exudative pleura disease, pleura fibrosis, lung fibrosis, and pericarditis are seen. Clinical improvement and normalization of X-ray findings are normally seen soon after cabergoline withdrawal. It appears that the dose typically used for treatment of hyperprolactinemia is too low to cause this type of side effects. In a combination study with 2,000 patients also treated with levodopa, the incidence and severity of side effects was comparable to monotherapy.
- It is not known whether cabergoline will harm an unborn baby.
- Pathological gambling, increased libido, hypersexuality, compulsive spending or buying, binge eating and compulsive eating can occur in patients treated with dopamine agonists including Cabaser (see section 4.4).
- If your symptoms are severe, call 911 or go to the nearest emergency room right away.
- No information is available about the interaction between cabergoline and other ergot alkaloids; therefore, the concomitant use of these medications during long-term treatment with cabergoline is not recommended.
- Cabergoline requires slow dose titration (2–4 weeks for hyperprolactinemia, often much longer for other conditions) to minimize side effects.
- During the first days of cabergoline administration, patients should be cautioned about re-engaging in activities requiring rapid and precise responses such as driving an automobile or operating machinery.
Division of the weekly dose into multiple administrations is advised when doses higher than 1 mg per week are to be given since the tolerability of doses greater than 1 mg taken as a single weekly dose has been evaluated only in a few patients. Since in clinical studies cabergoline has been mainly administered with food and since the tolerability of this class of compounds is improved with food, it is recommended that cabergoline be preferably taken with meals for all the therapeutic indications. This also keeps your body from releasing prolactin, which helps decrease your prolactin levels. Usually your doctor will listen to your heart before starting cabergoline treatment, and they may arrange an echocardiogram heart scan. It is very unusual for cabergoline to cause clinically significant heart problems, but you should alert your doctor if you developed shortness of breath or ankle swelling. All patients must undergo a cardiovascular evaluation, including echocardiogram, to assess the potential presence of asymptomatic valvular disease.
What other drugs will affect cabergoline?
Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable for you to take with your prescribed medicines. If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. It can cause dizziness, especially during the first few days of treatment. If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.
More common side effects
Don’t take this drug again if you’ve ever had an allergic reaction to it. Examples of drugs that can cause interactions with http://www.matset.com.tr/omnadren-250-mg-jelfa-online-in-berlin-der/ are listed below. To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.
Cabergoline is considered the best tolerable option for hyperprolactinemia treatment although the newer and less tested quinagolide may offer similarly favourable side effect profile with quicker titration times. This is not a complete list of side effects and others may occur. You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking cabergoline. Follow all directions on your prescription label and read all medication guides or instruction sheets. The information in this leaflet is for guidance purposes only and is in no way intended to replace professional clinical advice by a qualified practitioner.